Wet Cupping Therapy as A Complementary Intervention for Blood Glucose Reduction: Pre-Experimental Study

Authors

DOI:

https://doi.org/10.23917/bik.v19i1.12526

Keywords:

cupping therapy, blood glucose, Diabetes Mellitus

Abstract

Diabetes mellitus is a metabolic disease characterized by persistently elevated blood glucose levels and is a significant global public health problem. Wet cupping therapy is a complementary therapy that supports glycemic control, although community-based evidence is still very limited. This study was conducted to examine the short-term impact of wet cupping therapy on blood glucose levels in adults. This study used a pre-experimental, single-group pre-test-post-test design and was conducted in Wirobrajan Village, Yogyakarta, Indonesia, in April 2025. Thirty adults aged 26-45 years who were not receiving glucose-lowering medication were recruited using quota sampling. Blood glucose levels were measured before and immediately after one wet cupping therapy session. A paired-sample t-test with a significance level of p < 0.05 was used to look at the data. The mean blood glucose level dropped from 131 mg/dL before the intervention to 117 mg/dL after, a difference of 14.2 mg/dL. This drop was statistically significant (p = 0.0001). These findings indicate that wet cupping therapy significantly reduces short-term blood glucose levels in adults. Wet cupping therapy can be considered a complementary intervention for glycemic control. However, further randomized controlled trials are needed to confirm these findings.

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References

ADA. (2024). Standards of Medical Care in Diabetes. Diabetes Care, 46(Supplement 1), S1–S291. https://doi.org/10.2337/dc23-Sintesi

Al-Bedah, A. M. N., Khalil, M. K. M., Elolemy, A. T., & Hussein, A. A. (2022a). Hijama (wet cupping therapy): Indications, safety, and evidence-based perspective. Journal of Integrative Medicine, 20(1), 1–9. https://doi.org/10.1016/j.joim.2021.10.003

Al-Bedah, A. M. N., Khalil, M. K. M., Elolemy, A. T., & Hussein, A. A. (2022b). Hijama (wet cupping therapy): Indications, safety, and evidence-based perspective. Journal of Integrative Medicine, 20(1), 1–9. https://doi.org/10.1016/j.joim.2021.10.003

Association, W. M. (2022). World Medical Association Declaration of Helsinki: Ethical principles for medical research involving human subjects. JAM A, 327(7), 637–644. https://doi.org/10.1001/jama.2022.1610

Boddy, C., & Boddy, J. (2023). Sampling in health research. Journal of Clinical Nursing, 32(1–2), 12–20. https://doi.org/10.1111/jocn.16225

Bukhari, M. I. (n.d.). Shahih al-Bukhari. Hadith No. 5683.

Chow, S. C., Shao, J., Wang, H., & Lokhnygina, Y. (2018). Sample size calculations in clinical research (3rd ed.). Chapman dan Hall/CRC. https://doi.org/10.1201/9781315183084

Ebrahim, N., Hashem, M., & El-Masry, R. (2018). Therapeutic effects of wet cupping therapy in patients with type 2 diabetes mellitus. Journal of Advanced Research, 8(6), 687–695. https://doi.org/10.1016/j.jare.2017.09.001

El Sayed, N., Mostafa, R., & Farouk, H. (2021). Wet cupping therapy for blood glucose regulation: Evidence from clinical studies. Journal of Complementary and Integrative Medicine, 18(1), 12–20. https://doi.org/10.1515/jcim-2020-0215

Farhadi, K., Schwebel, D. C., Saeb, M., Choubsaz, M., Mohammadi, R., & Ahmadi, A. (2016). The effectiveness of wet cupping for nonspecific low back pain in Iran: A randomized controlled trial. Complementary Therapies in Medicine, 24, 1–6. https://doi.org/10.1016/ j.ctim.2016.02.007

Faul, F., Erdfelder, E., Buchner, A., & Lang, A. G. (2009). Statistical power analyses using G*Power 3.1: Tests for correlation and regression analyses. Behavior Research Methods, 41(4), 1149–1160. https://doi.org/10.3758/BRM.41.4.1149

Gray, J. R., Grove, S. K., & Sutherland, S. (2023). The practice of nursing research: Appraisal, synthesis, and generation of evidence. Elsevier., 9th ed.

Guyton, A. C., & Hall, J. E. (2021). Textbook of medical physiology. Elsevier., (14th ed.).

ITBI. (2020). Ikatan Terapis Bekam Indonesia(ITBI).

Kim, J. I., Lee, M. S., Lee, D. H., & Ernst, E. (2019). Cupping for treating pain: A systematic review. Evidence-Based Complementary and Alternative Medicine, 1–10. https://doi.org/ 10.1155 2019/8478291

Li-Kung Wu, Yi-Chen Chen, C.-S. H. (2024). The efficacy and safety of cupping as complementary and alternative therapy for metabolic syndrome: A systematic review and meta-analysis. Medicine (Baltimore), 102(13), e33341. https://doi.org/10.1097 /MD.0000000000033341

Li, H., Wang, J., & Zhang, X. (2022). Wet cupping therapy and glycemic control: A systematic review and meta-analysis. Evidence-Based Complementary and Alternative Medicine. https://doi.org/10.1155/2022/8823902

Liu, W., Zhang, Y., Wang, Y., & Li, Q. (2022). Efficacy and safety of wet cupping therapy for the treatment of type 2 diabetes mellitus: A systematic review and meta-analysis. Complementary Therapies in Clinical Practice, 49, 101651. https://doi.org/10.1016/ j.ctcp.2022.101651

Liu, W., Zhang, Y., Wang, Y., & L. (2022). Efficacy and safety of wet cupping therapy for the treatment of type 2 diabetes mellitus: A systematic review and meta-analysis. Complementary Therapies in Clinical Practice, 46. https://doi.org/10.1016/j.ctcp.2022.101651

Nik Husain, R., Mohd Hairon, S., Mohd Zain, R. (2020). The effects of wet cupping therapy on fasting blood sugar, renal function parameters, and endothelial function: A single-arm intervention study. Oman Medical Journal, 35(2), e108. https://doi.org/10.5001/omj.2020.26

Polit, D. F., & Beck, C. T. (2021). Generating and assessing evidence for nursing practice. Wolters Kluwer. Nursing Research, (11th ed.).

Qureshi, N. A., Ali, G. I., & Alqahtani, A. (2020). Integration of cupping therapy within modern medicine: Current evidence and future perspective. Integrative Medicine Research, 9(3). https://doi.org/10.1016/j.imr.2020.100449

Sherwood, L. (2020). Human physiology: From cells to systems. Cengage Learning., (10th ed.).

Syaikhu. (2008). Mukjizat pengobatan bekam Nabi: Studi ilmiah dan praktik bekam kesehatan Islam. Yogyakarta: Pustaka Thibbun Nabawi.

Tao, J., Zhao, P., Mo, T., Zhao, R., Yang, N., Lee, M. S., Liu, J., & Cao, H. (2020). Key elements that determine the efficacy of cupping therapy: A bibliometric analysis and review of clinical studies. Journal of Traditional Chinese Medical Sciences, 7(4), 345–354. https://doi.org/10.1016/j.jtcms.2020.11.001

Wu, L.-K., Chen, Y.-C., Hung, C.-S., et al. (2023). The efficacy and safety of cupping as complementary and alternative therapy for metabolic syndrome: A systematic review and meta-analysis. Medicine (Baltimore), 102(13), e33341. https://doi.org/10.1097 /MD.0000000000033341

Wulandari, R. (2015). Pengaruh terapi bekam terhadap penurunan glukosa darah di Karangmalaya Sragen. Jurnal Ilmiah Kesehatan, 6(2), 25–32.

Xiong, J., Zhang, Y., & Zhang, X. (2021). Effects of cupping therapy on anxiety and quality of life: A meta-analysis. Journal of Integrative Medicine, 19(4), 316–324. https://doi.org/10.1016 /j.joim.2021.04.005

Zhang, L., Zheng, Y., & Qiao, Y. (2021a). Effect of cupping therapy on blood glucose in patients with type 2 diabetes: A randomized controlled trial. Evidence-Based Complementary and Alternative Medicine. https://doi.org/10.1155/2021/9945631

Zhang, L., Zheng, Y., & Qiao, Y. (2021b). Effect of cupping therapy on blood glucose in patients with type 2 diabetes: A randomized controlled trial. Evidence-Based Complementary and Alternative Medicine, 1. https://doi.org/10.1155/2021/9945631

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Submitted

2025-08-20

Accepted

2025-12-23

Published

2026-01-31

How to Cite

Mahfud, M., Sarwadhamana, R. J., Muhammad, D. F., Almubarok, A. Z., & Arroyan, A. (2026). Wet Cupping Therapy as A Complementary Intervention for Blood Glucose Reduction: Pre-Experimental Study. Jurnal Berita Ilmu Keperawatan, 19(1), 111–120. https://doi.org/10.23917/bik.v19i1.12526

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