Physical Test of Fennel Leaf Ethanol Extract Gel Formulation (Foenicullum vulgare mill.)
DOI:
https://doi.org/10.23917/jnhm.v6i1.15935Keywords:
Ethanol Extract, Fennel Leaves, Gel Formulation, Physical TestAbstract
Fennel is a plant that is widely used as food and traditional medicine, the parts of the plant that are often used are the fruit and leaves. This plant has many pharmacological activities, including being antibacterial. The aim of this research was to test the physical properties of ethanol extract gel preparations of fennel leaves with various formulas. The method used in this research is experimental research carried out in the laboratory using four formulas (F1, F2, F3 and F4) with different concentrations of fennel leaf extract from 1%, 2%, 3% and 4%. The research results obtained in the organoleptic tests met the requirements for each formula, while the physical tests (homogeneity, pH, viscosity, spreadability and stickiness tests) for Formula 1 (1%) and Formula 2 (2%) met the physical test requirements. Meanwhile, in Formula 3 (3%) and 4 (4%) the physical tests in the homogeneity, viscosity and adhesion tests did not meet the requirements and for the pH test and spreadability test they met the requirements. The results of statistical tests using the ANOVA test on the viscosity, adhesion and spreadability tests had significant differences (p<0.05). These results can be concluded that formulas 1 and 2 are preparations that meet the requirements as gel preparations compared to formulas 3 and 4.
Downloads
References
Abdul, A. (2020). Uji Aktivitas Antioksidan Ekstrak Etanol Daun Adas (Foeniculum vulgare Mill) Dengan Metode DPPH Dan FRAP. Pharmed: Journal of Pharmaceutical Science and Medical Research, 3(2), 43–54.
Abdul, A., & Qonitah, F. (2019). Pengaruh Pemberian Ekstrak Etanol Daun Adas terhadap Kadar Hormon Prolaktin pada Tikus Betina Post Partum. Jurnal Farmasetis, 8(2), 39–44. https://doi.org/10.32583/farmasetis.v8i2.616
Abdul, A., & Qonitah, F. (2020). Uji Kandungan Fenolik Dan Flavonoid Total Ekstrak Etanol Daun Dan Buah Adas (Foeniculum Vulgare Mill) Dengan Metode Spektrofotometer Visibel (Tampak) Serta Skrining Fitokimia. Prosiding Pertemuan Ilmiah Daerah IAI PD JawaTengah.
Abdul, A., Qonitah, F., & _ P. (2021). Antibacterial Activity Of Fennel Leaves Ethanol Extract (Foeniculum vulgare Mill) Against Pseudomonas Aeruginosa. Jurnal Farmasi Sains Dan Praktis, 7(2), 154–162. https://doi.org/10.31603/pharmacy.v7i2.4873
Abdul, A., Safitri, F. W., & Purbowati, R. (2020). Efek Pemberian Ekstrak Etanol Buah Adas (Foenicullum vulgare Mill.) terhadap Kadar Hormon Prolaktin Tikus Putih Betina Post Partum. Pharmacon: Jurnal Farmasi Indonesia, 17(1), 1–8. https://doi.org/10.23917/pharmacon.v17i1.9245
Allen, L., & Ansel, H. C. (2013). Ansel’s pharmaceutical dosage forms and drug delivery systems. Lippincott Williams & Wilkins.
Anam, C. (2010). Ekstraksi oleoresin jahe (Zingiber officinale) kajian dari ukuran bahan, pelarut, waktu dan suhu. Mapeta, 12(2).
Astutik, A. P., & Qonitah, F. (2023). Formulasi Handbody lotion Ekstrak Kulit Buah Naga Merah (Hylocereus monacanthus) Sebagai Tabir Surya. Jurnal Farmasi Sains Dan Teknologi, 1(01), 6–13.
Badgujar, S. B., Patel, V. V., & Bandivdekar, A. H. (2014). Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology. BioMed Research International, 2014, 1–32. https://doi.org/10.1155/2014/842674
Departemen kesehatan RI. (2008). Farmakope Herbal Indonesia, Edisi I. Jakarta: Departemen Kesehatan RI, 78–80.
Di Napoli, M., Castagliuolo, G., Badalamenti, N., Maresca, V., Basile, A., Bruno, M., Varcamonti, M., & Zanfardino, A. (2022). Antimicrobial, antibiofilm, and antioxidant properties of essential oil of Foeniculum vulgare Mill. leaves. Plants, 11(24), 3573.
Gulfraz, M., Mehmood, S., Minhas, N., Jabeen, N., Kausar, R., Jabeen, K., & Arshad, G. (2008). Composition and antimicrobial properties of essential oil of Foeniculum vulgare. African Journal of Biotechnology, 7(24).
Hartanto, E. S., Lestari, N., & Silitonga, R. F. (2020). Ekstraksi dan Identifikasi Daun Adas Sayur (Artemisia cf. scoparia Waldst. & Kit.) untuk Sediaan Herbal. Warta IHP, 37(1), 1–6.
Kridati, E. M., Prihastanti, E., & Haryanti, S. (2012). Rendemen Minyak Atsiri dan Diameter Organ serta Ukuran Sel Minyak Tanaman Adas (Foeniculum vulgare Mill) yang Dibudidayakan di Kabupaten Semarang dan Kota Salatiga. ANATOMI Dan FISIOLOGI, 20(1), 1–17.
Marlina, S. D. (2015). Skrining Fitokimia dan Analisis Kromatrogafi Lapis Tipis Kompnen Kimia Buah Labu Siam (Sechium edule Jacq. Swartz) Dalam Ektrak Etanol. Jurusan Biologi FMIPA UNS Surakarta.
Pambudi, R. R. K., & Ahwan, A. (2023). Formulasi Nanoemulgel Ekstrak Biji Kopi Robusta (Coffea canephora Pierre) Dengan Variasi Gelling Agent Sebagai Antioksidan. Jurnal Farmasi Indonesia, 20(1), 11–23.
Praptiwi, P., Iskandarsyah, I., & Kuncari, E. S. (2014). Evaluasi, uji stabilitas fisik dan sineresis sediaan gel yang mengandung minoksidil, apigenin dan perasan herba seledri (Apium graveolens L.). Indonesian Bulletin of Health Research, 42(4), 20088.
Pratama, W. A., & Zulkarnain, A. K. (2015). Uji SPF in vitro dan sifat fisik beberapa produk tabir surya yang beredar di pasaran. Majalah Farmaseutik, 11(1), 275–283.
Puspitasari, L., Swastini, D. a., & Arisanti, C. I. a. (2013). Skrining Fitokimia Ekstrak Etanol 95% Kulit Buah Manggis (Garcinia mangostana L .). Garuda Portal, 961, 5.
Puspitasary, K., Wijayanti, A. N., & Indarto, I. (2023). Evaluasi Formula dan Uji Aktivitas Antibakteri Gel Ekstrak Daun Johar (Cassia siamea L.) dengan Beberapa Perbandingan Gom Arab dan Tragakan Terhadap Staphylococcus aureus. Jurnal Farmasi Sains Dan Teknologi, 1(01), 25–32.
Rahma, A. A., Ahwan, & Ariastuti, R. (2023). Analisis Kandungan Fenolik Total pada Fraksi Ekstrak Etanol Daun Adas (Foeniculum vulgare mill) dengan Metode Partisi Bertingkat [Skripsi]. Universitas Sahid Surakarta.
Rahmawati, A. D., Styawan, A. A., & Hidayati, N. (2018). Uji Sifat Fisis Gel Ekstrak Etanol Batang Brotowali (Tinospora Crispa, L) Dengan Variasi Konsentrasi Carbopol Dan Propilenglikol. MOTORIK Jurnal Ilmu Kesehatan, 13(1), 1–10.
Susilo, M. Y. (2019). Potensi buah adas (Foeniculum vulgare) sebagai gastroprotektor. Jurnal Ilmiah Kesehatan Sandi Husada, 8(2), 346–349.
Susilowati, A., Mulyawan, A. E., & Putri, T. W. (2019). Antioxidant Activity of the Sea Grape (Caulerpa racemasa) Used as an Antioxidant Lotion. Oriental Journal of Chemistry, 35(4).
Wahyuni, W., Ahwan, A., & Qonitah, F. (2021). Identifikasi Senyawa Hasil Ekstrak Etanol Daun Adas (Foeniculum vulgare mill) dengan Skrining Fitokimia dan Fourier Transform Infra-Red (FT-IR). Journal of Pharmaceutical Science and Medical Research, 4(2), 55–64.
Whika, F. D., Leni, R., & Ismi, R. (2017). Rendemen dan Skrining Fitokimia pada Ekstrak Daun Sanseviera sp. Jurnal Penelitian Pertanian Terapan, 17(3), 197–202.
Wijayanti, N., Astuti, K. W., Putra, I., Prasetia, I., Darayanthi, M. Y. D., Nesa, P., Wedarini, L. D. S., & Adhiningrat, D. N. P. (2015). Profil Stabilitas Fisika Kimia Masker Gel Peel-Off Ekstrak Kulit Buah Manggis (Garcinia mangostana L.). Jurnal Farmasi Udayana, 4(1), 279692.
Zulkarnain, A. K., Susanti, M., & Lathifa, A. N. (2013). Stabilitas fisik sediaan lotion o/w dan w/o ekstrak buah mahkota dewa sebagai tabir surya dan uji iritasi primer pada kelinci. Traditional Medicine Journal, 18(3), 141–150.
Submitted
Accepted
Published
Issue
Section
License
Copyright (c) 2026 Ahwan Abdul, Enjelina Sinta Mei, Diana, Hafidz Rosyadah, Fathin Salsabila
This work is licensed under a Creative Commons Attribution 4.0 International License.
