Article Review: Herbs for Bone Growth Process
DOI:
https://doi.org/10.23917/pharmacon.v23i1.7584Keywords:
Bone Growth, Chondrocytes, Herbs; Osteoblasts, Osteoclasts, OsteocytesAbstract
The process of bone growth occurs rapidly in childhood and stops when entering the puberty phase. Currently, stunted bone growth, known as stunting, is a health problem in the world. There is no drug that can specifically help bone growth. Likewise, the use of herbal plants for bone growth is still limited, so further research needs to be carried out to explore plants that have benefits to help increase bone growth. For this reason, the aim of writing this review article is as a basis for identifying herbal plants that can influence bone growth. So that the active compounds in related herbal plants can be developed to make new herbal medicinal products for stunted bone growth. Literature was searched using the scientific databases ScienceDirect, Pubmed, MDPI using several keywords "herbal medicine for bones" and "osteogenic activity in herbal plants". The results obtained were 18 articles that met the inclusion criteria. From these 18 articles, 11 active compounds were obtained, namely Osthole, Levistolide A, Calycosin-7-O-β-glucoside, Cistanoside A, Icariin, Naringenin, Wedelolactone, Ugonin L, Ligustroflavone, Ginsenosides, Puerarin which have the potential to help the bone growth process.
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